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See full prescribing information for VALACYCLOVIR TABLETS. Valacyclovir hydrochloride is a nucleoside analogue DNA polymerase inhibitor indicated for: The efficacy and safety of valacyclovir tablets have not been established in immunocompromised patients other than for the suppression of genital herpes in HIV-infected patients. Several antiviral medicines—acyclovir, valacyclovir , and famciclovir—are available to treat shingles and shorten the length and severity of the illness. Co-infection with HSV increases the risk of perinatal HIV transmission in women who had a clinical diagnosis of genital herpes during pregnancy.
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