Low Dose Naltrexone (LDN)


Is LDN For You?

Low Dose Naltrexone (LDN) has been used in the treatment of autoimmune diseases in the USA since 1985.  Naltrexone’s typical use is to treat addiction to opiate drugs such as heroin or morphine. The dose used for that purpose is usually 50 to 300mg daily.  In the case of LDN, the starting dose can be as low as 0.5mg.

How does it work? By boosting endorphin levels.  Technically, endorphins are peptides produced in the brain and adrenal glands.   You may know and feel them as your body’s mechanism for pain relief and enhancing your sense of well-being. They are also highly impactful on the immune system, which is critical as to why LDN works in many autoimmune situations.  

Bernard Bihari, MD, was the the first to discoverer the major clinical effects of low dose naltrexone. A private practitioner in Manhattan, Dr. Bihari was a Board-certified specialist in Psychiatry and Neurology.  He passed away in 2010, but not before completing numerous clinical studies on LDN and its successful use with a wide variety of conditions and diseases.

Some of the Conditions where LDN can be of benefit:

  •  Addison’s Disease
  • Cancers
  • Celiac disease
  • Chronic Fatigue Syndrome (CFS)
  • Crohns Disease
  • Cushing’s Syndrome
  • Endometriosis
  • Fibromyalgia
  • Gastritis
  • Graves’ disease
  • Hashimoto’s
  • HIV
  • Infertility
  • Lou Gehrig’s disease (ALS)
  • Lyme Disease
  • Mixed Connective Tissue Disease
  • Multiple Sclerosis (MS)
  • Myasthenia gravis
  • Parkinson’s Disease
  • Progressive inflammatory neuropathy
  • Psoriasis
  • Rheumatoid arthritis
  • Sjögren’s syndrome
  • Ulcerative colitis
  • Vasculitis

Doses vary for each condition, and follow up monitoring with your doctor is required to determine the appropriate levels for you.

Revolution Health Medical Center doctors use LDN as part of our integrative approach.  Once prescribed by us, it is then filled by a reputable compounding pharmacy.  We cannot emphasize enough that LDN should not be purchased online from private sellers.  Repeated tests have shown that LDN obtained in this manner does not contain the appropriate medicine and may have an adverse affect on your health.

Articles of Interest on LDN

The Neuroinflammation Man: Jarred Younger on Inflammation, Fibromyalgia and Chronic Fatigue Syndrome

LDN; How does it work?  (video)

Pradeep Chopra MD–LDN and Chronic Pain

LDN and Fibromyalgia

Learn more about or purchase The LDN Book.

The video below discusses LDN.  It was done outside of the US, so some of the information is not US specific.  However, the discussion of the impact on patients and positive impact on health issues is pertinent worldwide.