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Fluvoxamine
Clinical data
Trade namesFaverin, Fevarin, Floxyfral, Dumyrox, Luvox
AHFS/Drugs.comMonograph
MedlinePlusa682275
Pregnancy categoryC
Routes of administrationOral (tablets)
ATC codeN06AB08 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only
Bioavailability53% (90% confidence interval: 44–62%) [1]
Protein binding80% [1]
MetabolismHepatic (via cytochrome P450 enzymes. Mostly via oxidative demethylation) [1]
Elimination half-life12–13 hours (single dose), 22 hours (repeated dosing) [1]
ExcretionRenal (98%; 94% as metabolites, 4% as unchanged drug) [1]

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